In tip 0484, I described how to disable the Windows key.

In Windows 2000, the Windows logo key will open the Start menu. The following combinations are supported by default:

Windows logo key+E:  Starts Windows Explorer                              Windows logo key+R:  Opens the Run dialog box                              Windows logo key+F:  Opens the Search menu                              Windows logo key+U:  Starts Utility Manager                              Windows logo key+F1: Starts Windows Help                              Windows logo key+F3: Opens the Search menu.
You can disable the 'Windows logo key+E' combination by enabling the Disable programs on Settings menu Group Policy at User Configuration\AdministrativeTemplates\Start Menu and Taskbar.

NOTE: Enabling the Disable programs on Settings menu Group Policy will remove the following from the Settings menu:

Control Panel                              Network and Dialup Connections                              Printers
With the policy enabled, pressing the 'Windows logo key+E' displays:

This operation has been cancelled due to restrictions in effect on this computer. Please contact your system administrator.

NOTE: All other Windows logo key combinations will continue to work.