When Windows 2000 wakes from standby, you receive:
Unsafe Removal of Device
You have unplugged or ejected a device without stopping it which can cause your computer to crash and lose valuable data.
Please use the hotplug icon in the status bar to safely remove devices before unplugging them.
This behavior will occur if your computer has a USB 1.1 hub AND your keyboard has a USB 1.1 hub AND you connect a high-speed USB device, like a CD drive, to the keyboard's USB hub.
To workaround this problem, DO NOT use the keyboard's USB hub. Connect the high-speed device to the computer's USB port, or to an external USB hub.