If you are running out of room to store locally cached profiles, in %SystemRoot%\Profiles\ on your workstation, and you want to store as many as possible, you can configure the ProfileImagePaths on the workstation.

See tips 295, 368, and 679.

NOTE: If you don't want to store locally cached profiles, see tip 106.

Use Regedt32 to navigate to:

HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows NT\CurrentVersion\ProfileList

For each user who has logged on, there will be a SID sub-key and a Value Name of ProfileImagePath.

Change the string value to point to a folder on another partition.

Copy the profiles you want to keep from %SystemRoot%\Profiles\ to the new location and remove them from %SystemRoot%\Profiles. Remove cached profiles that you don't want to keep.

Shutdown and restart the workstation.

NOTE: If you copy the profile, your user may receive a "locally cached profile is newer" message. You don't have to copy the profile as the next user logon will re-cache it. If you don't copy it, delete the old one from %SystemRoot%\Profiles\.