If you have some extra RAM and an active file system, you can speed up file system activity by increasing the IoPageLockLimit from the default 512K bytes to 4096K bytes or more. Edit:
HKEY_LOCAL_MACHINE\System\CurrentControlSet\Control\Session Manager\Memory Management
IoPageLockLimit type REG_DWORD Default: 512K
This entry is the maximum number of bytes that can be locked for I/O operations. When the value is 0, the system defaults to 512K. The largest value is based on the amount of memory in your system. You MUST limit this entry to:
Less than 64 MB Physical memory minus 7 MB
64 MB–500 MB Physical memory minus 16 MB
512 MB and greater Physical memory minus 64 MB
Before making changes, get a baseline by using performance monitor for a representative period of time. Make your changes in small increments and measure performance after each change.